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In the SURMOUNT-5 study, people who used Zepbound lost 20.2% of body weight over 72 weeks, compared to 13.7% loss in those who used Wegovy (which contains the same active ingredient as Ozempic but at a slightly higher maximum dose)

Elevated circulating levels of OPN, a pro-inflammatory cytokine with a role in immune cell recruitment (240), have been associated with increased CV disease risk in patients with T2D (241)

GLP-1 is naturally produced by the gastrointestinal system to increase insulin production, lower glucagon secretion, target areas in the brain that regulate appetite and slow intestinal motility leading to feeling of fullness

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